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产品简介 品牌 MedChemExpress (MCE) 货号 HY-L0069V 供货周期 现货     Serine hydrolase library is a library of 12,040 precisely selected compounds able to form covalent bonds with catalytic Serine residue.
详细介绍 Serine Hydrolase Library

Serine hydrolase library is a library of 12,040 precisely selected compounds able to form covalent bonds with catalytic Serine residue.

Description & Advantages:

? A unique library of 12,040 diverse compounds able to form covalent bonds with catalytic serine residue.

? Serine hydrolases are one of the largest known enzyme classes comprising approximately ~200 enzymes or 1% of the genes in the human proteome.

? The main criteria of the selection was presence of the electrophilic group (eg. CN, epoxide, carbonyl etc.) which can provide the key interaction with serine in the active site.

? No PAINS (Pan Assay Interference Compounds), only medchem friendly compounds.

? Structurally diverse.

? Molecular properties: 100% Ro5 compliant, and 99.5 % lead-like.

? NMR and HPLC validated to ensure high purity and quality.

? All compounds can be readily followed with analogues either from stock or from new syntheses.

? Databases and compounds are provided by Enamine.

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